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Realization
of a three-dimensional photonic topological insulator
A three-dimensional photonic topological insulator
is presented, made of split-ring resonators with strong
magneto-electric coupling, which has an extremely wide topological
bandgap, forbidding light propagation.
Yihao Yang, Zhen Gao, Haoran Xue et al.
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Structures
of an RNA polymerase promoter melting intermediate elucidate DNA
unwinding
Cryo-electron microscopy structures of bacterial
RNAP–promoter DNA complexes, including structures of partially
melted intermediates, suggest a universally conserved common mechanism
for promoter DNA opening prior to gene expression.
Hande Boyaci, James Chen, Rolf Jansen et al.
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A
second source of repeating fast radio bursts
The CHIME/FRB Collaboration
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Chromosomes
come together to help mice distinguish odours
A study shows that a multi-chromosomal hub assembles
in mouse olfactory neurons to ensure that only one odour-sensing
receptor is expressed in each neuron — a feature essential to odour
discrimination.
François Spitz
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Protein
modification fine-tunes the cell’s force producers
Identification of the enzyme that catalyses a
site-specific modification of the protein actin reveals how this
change modulates the function of the cell’s force-producing
machinery.
Pekka Lappalainen
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Mobile
PEAR transcription factors integrate positional cues to prime
cambial growth
Radial growth in the roots of Arabidopsis,
which is mediated by gene expression activated by the mobile PEAR1
and PEAR2 transcription factors, is initiated around
protophloem-sieve-element cell files of procambial tissue.
Shunsuke Miyashima, Pawel Roszak, Iris Sevilem et
al.
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FTSJ3
is an RNA 2′-O-methyltransferase recruited by HIV to avoid
innate immune sensing
HIV-1 uses the host protein FTSJ3 to methylate its
own genome, thereby evading detection by the innate immune system.
Mathieu Ringeard, Virginie Marchand, Etienne Decroly
et al.
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Plant-thickening
mechanisms revealed
In roots, stem cells in the cambium region form
vascular tissues needed for the long-distance transport of water
and nutrients. How these stem cells are specified and regulated has
now been illuminated.
Sebastian Wolf, Jan U. Lohmann
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Mitochondrial
complex III is essential for suppressive function of regulatory T
cells
Specific ablation of mitochondrial complex III
subunits in Treg cells in mice results in inflammatory
disease, altered Treg gene expression and defective Treg
function, indicating a key functional role for mitochondrial
complex III in Treg cells.
Samuel E. Weinberg, Benjamin D. Singer, Elizabeth M.
Steinert et al.
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High
levels of auxin signalling define the stem-cell organizer of the
vascular cambium
In the roots of Arabidopsis thaliana, cells
with xylem identity and high levels of auxin signalling function as
organizer cells that direct neighbouring vascular cambial cells to
act as stem cells.
Ondřej Smetana, Riikka Mäkilä, Munan Lyu et al.
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A
recurrent nova super-remnant in the Andromeda galaxy
A frequently recurring nova is surrounded by an
enormous cavity in space, produced as the nova’s ejecta ‘sweeps up’
the interstellar medium around the star after each eruption.
M. J. Darnley, R. Hounsell, T. J. O’Brien et al.
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Subcellular
transcriptomes and proteomes of developing axon projections in the
cerebral cortex
A subcellular sorting approach enables quantitative
analysis of subtypes of growth cones in the brain, and reveals
subcellular relationships between local mRNA and local proteomes in
developing projection neurons.
Alexandros Poulopoulos, Alexander J. Murphy,
Abdulkadir Ozkan et al.
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Observations
of fast radio bursts at frequencies down to 400 megahertz
The CHIME/FRB Collaboration
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LHX2-
and LDB1-mediated trans interactions regulate olfactory
receptor choice
Specific interchromosomal contacts in olfactory
sensory neurons form a super-enhancer that controls the expression
of a single olfactory receptor in each neuron.
Kevin Monahan, Adan Horta, Stavros Lomvardas
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Calicivirus
VP2 forms a portal-like assembly following receptor engagement
Cryo-electron microscopy structures of feline
calicivirus and its cellular receptor show that twelve copies of
the minor capsid protein VP2 form a portal-like assembly arranged
about a pore in the capsid shell.
Michaela J. Conley, Marion McElwee, Liyana Azmi
et al.
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The
surprisingly large neutron capture cross-section of 88Zr
The thermal neutron capture cross-section of 88Zr
is measured to be 861,000 ± 69,000 barns, the second-largest
neutron capture cross-section ever measured.
Jennifer A. Shusterman, Nicholas D. Scielzo, Keenan
J. Thomas et al.
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Disruption
of the Orion molecular core 1 by wind from the massive star θ1
Orionis C
Wind from the most massive star in the Trapezium
cluster in Orion has carved out a large and expanding cavity around
the cluster, bounded by a thin, 2,600-solar-mass shell.
C. Pabst, R. Higgins, J. R. Goicoechea et al.
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SETD3
is an actin histidine methyltransferase that prevents primary
dystocia
SETD3 methylates mammalian actin at His73, and SETD3
deficiency impairs stimulus-induced contraction in primary human
uterine smooth muscle cells and leads to maternal dystocia in mice.
Alex W. Wilkinson, Jonathan Diep, Shaobo Dai et
al.
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Applications now open
Nature Research is proud to launch the Nature Research
Awards for Driving Global Impact, supporting early-career
researchers making real-world impact.
In 2019 the Award focuses on brain sciences. Applications
are invited from early-career researchers making major
contributions in brain sciences.
Find out more and apply now
In partnership with:
Tencent
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De
novo design of potent and selective mimics of IL-2 and IL-15
A hyper-stable de novo protein mimic of
interleukin-2 computationally designed to not interact with a
regulatory T-cell specific receptor subunit has improved
therapeutic activity in mouse models of melanoma and colon
cancer.
Daniel-Adriano Silva, Shawn Yu,
Umut Y. Ulge et al.
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Structural
basis of Notch recognition by human γ-secretase
The cryo-electron microscopy structure of human
γ-secretase in complex with its substrate Notch reveals
pronounced structural rearrangements compared to the apo enzyme,
including formation of a β-sheet involving residues from both
enzyme and substrate.
Guanghui Yang, Rui Zhou, Qiang
Zhou et al.
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The
corona contracts in a black-hole transient
X-ray observations of the evolution of a
black-hole transient suggest a shrinkage of its corona, rather
than a change in the inner edge of the accretion disk.
E. Kara, J. F. Steiner, A. C.
Fabian et al.
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A
warped disk around an infant protostar
Observations at millimetre wavelengths reveal a
young protostar surrounded by a disk with two differently tilted
regions.
Nami Sakai, Tomoyuki Hanawa,
Yichen Zhang et al.
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The
ultrafast Einstein–de Haas effect
Femtosecond time-resolved X-ray diffraction
reveals that in the ultrafast demagnitization of ferromagnetic
iron, about 80% of the angular momentum lost from the spins is transferred
to the lattice on a sub-picosecond timescale.
C. Dornes, Y. Acremann, M.
Savoini et al.
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The
global distribution and trajectory of tidal flats
Analyses of over 700,000 satellite images to map
the global extent of tidal flats over the past thirty years, and
enable assessments of the status and likely future trajectories
of these coastal ecosystems.
Nicholas J. Murray, Stuart R.
Phinn, Michael DeWitt et al.
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Genomic
insights into the 2016–2017 cholera epidemic in Yemen
Isolates of the Vibrio cholerae O1 serotype
Ogawa from Yemen are from a single sublineage of the seventh
pandemic El Tor (7PET) lineage and are susceptible to several
commonly used antibiotics as well as to polymyxins.
François-Xavier Weill, Daryl
Domman, Elisabeth Njamkepo et al.
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Genomic
encoding of transcriptional burst kinetics
Allele-specific single-cell RNA sequencing
provides insights into transcription kinetics, with data
indicating that core promoter sequences affect burst size,
whereas enhancers mainly affect burst frequency.
Anton J. M. Larsson, Per
Johnsson, Michael Hagemann-Jensen et al.
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natureevents directory featured events
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Natureevents
Directory is the premier resource for scientists
looking for the latest scientific conferences, courses, meetings and
symposia. Featured across Nature Publishing Group journals and
centrally at natureevents.com
it is an essential reference guide to scientific events worldwide.
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