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VOLUME 355, ISSUE 6332
30th March 2017
 
Science Table of Contents
Research Summaries

This Week in Science
Editor summaries of this week's papers.

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Editors' Choice
Highlights of the recent literature.

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Editorial

Science for life
Bruce Alberts

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[10.1126/science.aan2924]
 

In Brief

News at a glance
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[10.1126/science.355.6332.1354]
 

In Depth

Science funders plunge into publishing
Martin Enserink

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[10.1126/science.355.6332.1357]
 

U.N. biodiversity group confronts cash crunch
Erik Stokstad

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[10.1126/science.355.6332.1358]
 

HIV infections are spiking among young gay Chinese
Kathleen McLaughlin

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[10.1126/science.355.6332.1359]
 

Enzymes offer waste-to-energy solution
Mark Peplow

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[10.1126/science.355.6332.1360]
 

Is the cell's garbage disposal sending messages?
Mitch Leslie

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[10.1126/science.355.6332.1361]
 

Dengue may bring out the worst in Zika
Jon Cohen

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[10.1126/science.355.6332.1362]
 

Circular RNAs hint at new realm of genetics
Kelly Servick

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[10.1126/science.355.6332.1363]
 

Feature

Deadly chemistry
Kathleen McLaughlin

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[10.1126/science.355.6332.1364]
 

Working Life

Creating our own community
Cecilia Sánchez , Anya Brown

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[10.1126/science.355.6332.1446]
 

Letters

Global roadless areas: Hidden roads
Alice C. Hughes

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[10.1126/science.aam6995]
 

Global roadless areas: Consider terrain
Ruidong Wu , Wenli Wang, Feiling Yang, Junjun Wang, Wei Wu, Yixin Diao, Peijun Hu

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[10.1126/science.aan0698]
 

Global roadless areas-Response
Pierre L. Ibisch , Nuria Selva

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[10.1126/science.aam9830]
 

Book Reviews

Mechanized creatures
Pooya Sareh , Mirko Kovac

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[10.1126/science.aam9075]
 

Cresting a gravitational wave
Adrian Cho

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[10.1126/science.aam9747]
 

Policy Forum

Looking backward to move regulations forward
Maureen Cropper , Arthur Fraas, Richard Morgenstern

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[10.1126/science.aaj1469]
 

Harnessing legal complexity
J. B. Ruhl , Daniel Martin Katz, Michael J. Bommarito II

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[10.1126/science.aag3013]
 

Perspectives

Can we protect island flying foxes?
Christian E. Vincenot , F. B. Vincent Florens, Tigga Kingston

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[10.1126/science.aam7582]
 

Breathing to inspire and arouse
Shahriar Sheikhbahaei , Jeffrey C. Smith

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[10.1126/science.aan1466]
 

How Cyanobacteria went green
Robert E. Blankenship

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[10.1126/science.aam9365]
 

Costimulation, a surprising connection for immunotherapy
Derek L. Clouthier , Pamela S. Ohashi

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[10.1126/science.aan1467]
 

Review

Biodiversity redistribution under climate change: Impacts on ecosystems and human well-being
Gretta T. Pecl , Miguel B. Araújo, Johann D. Bell, Julia Blanchard, Timothy C. Bonebrake, I-Ching Chen, Timothy D. Clark, Robert K. Colwell, Finn Danielsen, Birgitta Evengård, Lorena Falconi, Simon Ferrier, Stewart Frusher, Raquel A. Garcia, Roger B. Griffis, Alistair J. Hobday, Charlene Janion-Scheepers, Marta A. Jarzyna, Sarah Jennings, Jonathan Lenoir, Hlif I. Linnetved, Victoria Y. Martin, Phillipa C. McCormack, Jan McDonald, Nicola J. Mitchell, Tero Mustonen, John M. Pandolfi, Nathalie Pettorelli, Ekaterina Popova, Sharon A. Robinson, Brett R. Scheffers, Justine D. Shaw, Cascade J. B. Sorte, Jan M. Strugnell, Jennifer M. Sunday, Mao-Ning Tuanmu, Adriana Vergés, Cecilia Villanueva, Thomas Wernberg, Erik Wapstra, Stephen E. Williams

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[10.1126/science.aai9214]
 

Research Articles

Gene bivalency at Polycomb domains regulates cranial neural crest positional identity
Maryline Minoux , Sjoerd Holwerda, Antonio Vitobello, Taro Kitazawa, Hubertus Kohler, Michael B. Stadler, Filippo M. Rijli

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[10.1126/science.aal2913]
 

Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq
Andrew S. Venteicher , Itay Tirosh, Christine Hebert, Keren Yizhak, Cyril Neftel, Mariella G. Filbin, Volker Hovestadt, Leah E. Escalante, McKenzie L. Shaw, Christopher Rodman, Shawn M. Gillespie, Danielle Dionne, Christina C. Luo, Hiranmayi Ravichandran, Ravindra Mylvaganam, Christopher Mount, Maristela L. Onozato, Brian V. Nahed, Hiroaki Wakimoto, William T. Curry, A. John Iafrate, Miguel N. Rivera, Matthew P. Frosch, Todd R. Golub, Priscilla K. Brastianos, Gad Getz, Anoop P. Patel, Michelle Monje, Daniel P. Cahill, Orit Rozenblatt-Rosen, David N. Louis, Bradley E. Bernstein, Aviv Regev, Mario L. Suvà

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[10.1126/science.aai8478]
 

Reports

Surface changes on comet 67P/Churyumov-Gerasimenko suggest a more active past
M. Ramy El-Maarry , O. Groussin, N. Thomas, M. Pajola, A.-T. Auger, B. Davidsson, X. Hu, S. F. Hviid, J. Knollenberg, C. Güttler, C. Tubiana, S. Fornasier, C. Feller, P. Hasselmann, J.-B. Vincent, H. Sierks, C. Barbieri, P. Lamy, R. Rodrigo, D. Koschny, H. U. Keller, H. Rickman, M. F. A'Hearn, M. A. Barucci, J.-L. Bertaux, I. Bertini, S. Besse, D. Bodewits, G. Cremonese, V. Da Deppo, S. Debei, M. De Cecco, J. Deller, J. D. P. Deshapriya, M. Fulle, P. J. Gutierrez, M. Hofmann, W.-H. Ip, L. Jorda, G. Kovacs, J.-R. Kramm, E. Kührt, M. Küppers, L. M. Lara, M. Lazzarin, Z.-Yi Lin, J. J. Lopez Moreno, S. Marchi, F. Marzari, S. Mottola, G. Naletto, N. Oklay, A. Pommerol, F. Preusker, F. Scholten, X. Shi

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[10.1126/science.aak9384]
 

Controlled growth and form of precipitating microsculptures
C. Nadir Kaplan , Wim L. Noorduin, Ling Li, Roel Sadza, Laura Folkertsma, Joanna Aizenberg, L. Mahadevan

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[10.1126/science.aah6350]
 

Identification of single-site gold catalysis in acetylene hydrochlorination
Grazia Malta , Simon A. Kondrat, Simon J. Freakley, Catherine J. Davies, Li Lu, Simon Dawson, Adam Thetford, Emma K. Gibson, David J. Morgan, Wilm Jones, Peter P. Wells, Peter Johnston, C. Richard A. Catlow, Christopher J. Kiely, Graham J. Hutchings

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[10.1126/science.aal3439]
 

Arylation of hydrocarbons enabled by organosilicon reagents and weakly coordinating anions
Brian Shao , Alex L. Bagdasarian, Stasik Popov, Hosea M. Nelson

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[10.1126/science.aam7975]
 

Mars' atmospheric history derived from upper-atmosphere measurements of 38Ar/36Ar
B. M. Jakosky , M. Slipski, M. Benna, P. Mahaffy, M. Elrod, R. Yelle, S. Stone, N. Alsaeed

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[10.1126/science.aai7721]
 

Breathing control center neurons that promote arousal in mice
Kevin Yackle , Lindsay A. Schwarz, Kaiwen Kam, Jordan M. Sorokin, John R. Huguenard, Jack L. Feldman, Liqun Luo, Mark A. Krasnow

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[10.1126/science.aai7984]
 

Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites
M. Dawidowski , L. Emmanouilidis, V. C. Kalel, K. Tripsianes, K. Schorpp, K. Hadian, M. Kaiser, P. Mäser, M. Kolonko, S. Tanghe, A. Rodriguez, W. Schliebs, R. Erdmann, M. Sattler, G. M. Popowicz

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[10.1126/science.aal1807]
 

The whole-soil carbon flux in response to warming
Caitlin E. Hicks Pries , C. Castanha, R. C. Porras, M. S. Torn

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[10.1126/science.aal1319]
 

Rescue of exhausted CD8 T cells by PD-1-targeted therapies is CD28-dependent
Alice O. Kamphorst , Andreas Wieland, Tahseen Nasti, Shu Yang, Ruan Zhang, Daniel L. Barber, Bogumila T. Konieczny, Candace Z. Daugherty, Lydia Koenig, Ke Yu, Gabriel L. Sica, Arlene H. Sharpe, Gordon J. Freeman, Bruce R. Blazar, Laurence A. Turka, Taofeek K. Owonikoko, Rathi N. Pillai, Suresh S. Ramalingam, Koichi Araki, Rafi Ahmed

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[10.1126/science.aaf0683]
 

T cell costimulatory receptor CD28 is a primary target for PD-1-mediated inhibition
Enfu Hui , Jeanne Cheung, Jing Zhu, Xiaolei Su, Marcus J. Taylor, Heidi A. Wallweber, Dibyendu K. Sasmal, Jun Huang, Jeong M. Kim, Ira Mellman, Ronald D. Vale

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[10.1126/science.aaf1292]
 

Aging increases cell-to-cell transcriptional variability upon immune stimulation
Celia Pilar Martinez-Jimenez , Nils Eling, Hung-Chang Chen, Catalina A. Vallejos, Aleksandra A. Kolodziejczyk, Frances Connor, Lovorka Stojic, Timothy F. Rayner, Michael J. T. Stubbington, Sarah A. Teichmann, Maike de la Roche, John C. Marioni, Duncan T. Odom

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[10.1126/science.aah4115]
 

On the origins of oxygenic photosynthesis and aerobic respiration in Cyanobacteria
Rochelle M. Soo , James Hemp, Donovan H. Parks, Woodward W. Fischer, Philip Hugenholtz

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[10.1126/science.aal3794]
 

Technical Comments

Comment on "Outburst flood at 1920 BCE supports historicity of China's Great Flood and the Xia dynasty"
Wenxiang Wu , Junhu Dai, Yang Zhou, Quansheng Ge

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[10.1126/science.aal1278]
 

Comment on "Outburst flood at 1920 BCE supports historicity of China's Great Flood and the Xia dynasty"
Chun Chang Huang , Yali Zhou, Yuzhu Zhang, Yongqiang Guo, Jiangli Pang, Qiang Zhou, Tao Liu, Xiaochun Zha

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[10.1126/science.aak9657]
 

Response to Comments on "Outburst flood at 1920 BCE supports historicity of China's Great Flood and the Xia dynasty"
Qinglong Wu , Zhijun Zhao, Li Liu, Darryl E. Granger, Hui Wang, David J. Cohen, Xiaohong Wu, Maolin Ye, Ofer Bar-Yosef, Bin Lu, Jin Zhang, Peizhen Zhang, Daoyang Yuan, Wuyun Qi, Linhai Cai, Shibiao Bai

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[10.1126/science.aal1325]
 

New Products

New Products
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[10.1126/science.355.6332.1441]
 

First Release
 
First Release
Selected Science papers are published online ahead of print. Some editorial changes may occur between the online version and the final printed version.

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