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01/15/16 Volume 351, Issue 6270


In this week's issue:


Research Summaries


Editor summaries of this week's papers.

Highlights of the recent literature.


Editorial



In Brief


A roundup of weekly science policy and related news.



In Depth


Space

Primordial clouds show how giant stars forged the heavy elements that fill today's universe.


Neuroscience

$2 million fine for Lumosity is latest shot at claims of cognitive benefits from games and apps.


Scientific Publishing

ORCID gives every Smith and Wang a unique number.


Comparative Biology

Researchers broaden their focus beyond male anatomy.


Technology

Photonic technology boosts efficiency of warm, wasteful bulbs.


Scientific Community

University restricts his access to graduate students after upholding their complaints.



Feature


Particles consisting of four and five quarks make a comeback.


Some scientists see Nicaragua's plans for a Grand Canal as a boon for an ailing land; others predict ecological catastrophe.



Working Life



Letters






Books et al.


Neuroscience

Adaptations that gave our ancestors an evolutionary edge can cause major problems for modern humans


Medicine

Researchers tweak the genetic lottery for children with rare diseases


As of 1 January 2016, Science will no longer provide a weekly list of books received.



Perspectives


Infectious Disease

Criteria for disease causation must take microbial interactions into account


RNA

Peptides from long noncoding RNAs control a muscle calcium pump [Also see Report by Nelson et al.]


Genetics

Cap-independent translation by IRESs can occur from various locations in mRNA [Also see Research Article by Weingarten-Gabbay et al.]


Applied Optics

The emission of a terahertz laser is controlled by graphene carrier density [Also see Report by Chakraborty et al.]


Planetary Science

In situ measurements reveal details of the production and evolution of the lunar exosphere [Also see Report by Colaprete et al.]



Reviews



Research Articles


Strained rings are appended to compounds of pharmaceutical interest through the use of even more highly strained precursors.


Ribosomal translation of both human and viral RNAs does not always require scanning from the 5′ end. [Also see Perspective by Gebauer and Hentze]



Reports


A layer of graphene is used to control the emission spectrum of a laser. [Also see Perspective by Polini]


The Moon's tenuous atmosphere varies over each month and after meteoroid streams. [Also see Perspective by Dukes and Hurley]


Amino acids can reversibly complex with aldehydes and ketones to direct palladium-catalyzed formation of carbon-carbon bonds.


The most luminous supernova yet found was glimpsed in an unusual host galaxy.


Injuries to a mammoth carcass indicate that humans penetrated Siberia as far as 72°N 45,000 years ago.


Phytoplankton convert more sunlight to heat than to fluorescence or photosynthesis.


Songs that birds have already learned are preserved by inhibitory neurons that block further modifications.


A long noncoding RNA encodes a small peptide that activates a calcium pump regulating muscle contraction. [Also see Perspective by Payre and Desplan]


An energy-sensing kinase phosphorylates a mitochondrial membrane protein that initiates fragmentation.


Posttranscriptional modification of messenger RNAs (mRNAs) is prevalent in Drosophila and promotes mRNA translation.


Reactivation of fetal globin gene expression may enable treatment of hemoglobinopathies.



Technical Comments



New Products


A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.



From the AAAS Office of Publishing and Member Services


Business Office Feature

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