A roundup of weekly science policy and related news.

Prospect of heritable changes sparks questions about safety, ethics, and rationale.

Fibrous keratin can store a chemical record of pregnancies and stress.

Companies bet on a GPS technique and an agency shift to commercial data.

Speculative effort was destined to fail, critics say.

Isolated people recovering from conflict with settled neighbors in the Brazilian Amazon.

Meeting promotes ways to cut clinic visits and tests without compromising treatment.

Devices that monitor and coach users bring promise and peril to the science of behavior change.

The classic chemistry set gets a 21st-century upgrade

Two hundred years after her birth, a new exhibition explores the life of Ada Lovelace

A listing of books received at Science during the week ending 04 December 2015.

Overcoming legal and policy obstacles

Male prairie voles with poor memory skills are less faithful to their partners [Also see Report by Okhovat et al.]

Optical signal processing can help reduce noise in detection of ultrafast electrical pulses [Also see Report by Ataie et al.]

Superconducting two-dimensional materials are found to be remarkably robust [Also see Report by Lu et al.]

A high dose of vitamin C kills certain colon cancer cells [Also see Report by Yun et al.]

Tissues may use diverse mechanisms to replace lost cells

When atoms collide with metal surfaces, electron-hole pair excitations dissipate the adsorption energy [Also see Report by Bünermann et al.]

Combining the capacity to handle noise with probabilistic learning yields humanlike performance in a computational model.

An analytic framework extracts transition state characteristics in isomerizations directly from vibrational spectral data.

Understanding the organizing principles allows exhaustive enumeration of possible protein quaternary structure topologies.

Single transient signals can be detected even when buried within a noisy environment. [Also see Perspective by Vasilyev]

Control of the energy of an atomic hydrogen beam allowed measurement of its inelastic scattering from surfaces. [Also see Perspective by Brune]

Geodynamic modeling reveals a large viscosity increase in Earth's mid-mantle.

Transport measurements are used to reveal a superconducting state that is only weakly affected by an in-plane magnetic field. [Also see Perspective by Suderow]

A large glacier in northeast Greenland is retreating rapidly as air and ocean warm.

Technological advances allow direct imaging of neural spikes and dendritic voltage dynamics in live mice and flies.

Researchers' career patterns can provide a means to move knowledge from the university to the broader economy.

Trade-offs between fidelity and infidelity in prairie voles can promote heritable differences in the brain. [Also see Perspective by Robinson]

Two life-span-extending pathways in the worm converge to increase production of an enzyme in the intestine.

A signaling pathway is vulnerable to disruption by suitably timed input.

RNA polymerase is paused near the promoters of many genes, and Pol II-associated factor 1 plays a critical role in its release.

Individuals with cancers that have low mutation frequencies often harbor mutation-reactive T cells.

Cancer cells with certain mutations take up the oxidized form of vitamin C, which fatally disrupts their metabolism. [Also see Perspective by Reczek and Chandel]

On this week's show: Teaching computers to generalize the way humans do and a daily news round-up.

A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.