In this week's issue:
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| Research Summaries |
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Editor summaries of this week's papers. Highlights of the recent literature.
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| Editorial |
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| In Brief |
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A roundup of weekly science policy and related news.
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| In Depth |
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Fusion Energy Daniel Clery
Review notes progress but estimates "first plasma" will take 6 years longer than planned.
Infectious Diseases Martin Enserink After racing through Oceania last year, the Zika virus is now spreading in the Americas.
Biomedical Research Jocelyn Kaiser NIH announces plans to retire its last chimpanzees.
Science and Society Elizabeth Pennisi Antiparasite genes made to spread among lab insects.
Academic Misconduct Mara Hvistendahl Measures may not be enough to stem the tide, some fear.
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| Feature |
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Eli Kintisch After decades of failure, a new approach to negotiations has raised hopes that nations meeting in Paris will agree to meaningful climate steps.
Eli Kintisch Officials call the Paris talks a beginning, but what's the destination? Below are three possible future paths for annual global greenhouse gas emissions. Models suggest each would produce very different ranges of atmospheric greenhouse gas levels and warming in 2100. And all would cause the seas to rise for centuries after 2100.
Robert F. Service Denmark is striving to become the world's first carbon-neutral nation.
Priyanka Pulla India hopes that steps to limit climate change will also improve its citizens' lives. Critics say such "cobenefits" may be a pipe dream.
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| Working Life |
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| Letters |
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Hudson T. Pinheiro et al. Life in Science Rana Dajani
Patrick Schloss
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| Books et al. |
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Exhibition Giovanni Frazzetto A new exhibition explores how scientific advances are changing what it means to be human
Big Data Laura Stark A long-forgotten social science archive offers a lesson in responsible data management
Popular Science A listing of books received at Science during the week ending 20 November 2015.
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| Policy Forum |
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Energy and Environment Joanna I. Lewis et al.
Methodology standardization will improve comparability
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| Perspectives |
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Human Genome Charles Boone and Brenda J. Andrews Solar Fuels Ole Hansen et al. Transient photoreflectance spectroscopy reveals charge carrier dynamics in water splitting [Also see Report by Yang et al.]
Immunotherapy Alexandra Snyder et al. Intestinal microbes affect immunotherapy responses in mouse models of cancer [Also see Reports by Vétizou et al. and
Sivan et al.]
Applied Optics Natalia M. Litchinitser and Jingbo Sun Metamaterials are poised to transform nonlinear optics
Ecology Jacquelyn L. Gill Herbivore diversity plays a key role in grassland ecosystems [Also see Research Article by Hempson et al.]
Evolution Geerat Vermeij Evolutionary innovations are not always beneficial [Also see Report by McGee et al.]
Retrospective Catherine Nobes et al. The loss of a leading cell and cancer biologist
Retrospective Richard Marais A cell biologist's meticulous work drove the discovery of new cancer treatments
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| Association Affairs |
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Gavin Stern At the AAAS symposium, researchers searched for new avenues of public engagement to address the gap in climate change beliefs
Earl Lane
This year's winners included stories on the health impacts of urban violence, local signs of global climate change, and West Africa's Ebola epidemic
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| Reviews |
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Ji-Xin Cheng and X. Sunney Xie
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| Research Articles |
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Gareth P. Hempson et al. Census data reveal the ways that large herbivores impact vegetation and ecosystems across a continent. [Also see Perspective by Gill]
Xiaolong Jiang et al. The connections between more than 10,000 pairs of individually classified neurons in the visual cortex of adult mice are mapped.
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| Reports |
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Ye Yang et al. Reflection spectroscopy offers insights into the boost to charge separation conferred by TiO2 coatings on photoelectrodes. [Also see Perspective by
Hansen]
Matin Amani et al. Superacid treatment enhances the luminescence efficiency of monolayer molybdenum disulfide from 1% to >95%.
Soheil Ghanbarzadeh et al. Salt deposits in the Gulf of Mexico show evidence of deformation-driven fluid percolation.
Joshua Blumenstock et al. Metadata from individuals' phones can be used to predict aggregate-level characteristics such as access to electricity.
Matthew D. McGee et al. Jaw specialization in fish may have paradoxically reduced speciation in the African Great Lakes. [Also see Perspective by Vermeij]
Marie Vétizou et al. Gut microbes modulate the effectiveness of cancer immunotherapies in mice.
Ayelet Sivan et al. Gut microbes modulate the effectiveness of cancer immunotherapies in mice. [Also see Perspective by Snyder et al.]
Alexis Kaushansky et al. The hepatocyte EphA2 receptor is important for malaria parasite infection of the liver and is engaged by the parasite ligand P36.
Vincent A. Blomen et al. Systematic mutagenesis reveals essential genetic interactions required for human cells to keep growing. [Also see Perspective by Boone and Andrews]
Tim Wang et al. A comprehensive screen identifies genes required for normal and cancerous human cells to keep growing. [Also see Perspective by Boone and Andrews]
Luhan Yang et al. CRISPR-Cas genome editing is adapted to remove 62 copies of a retrovirus from the porcine genome.
Wolf Holtkamp et al. A small protein folds into a non-native form as it is synthesized on the ribosome before adopting its native shape.
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| Podcast |
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On this week's show: Bioengineering vocal cords and a roundup of daily news stories.
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| New Products |
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A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.
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