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Chemistry Ph.D. student Maureen McKeague and colleagues of Carleton University interpret a chemical technique for generating short segments of DNA that can bind to an amino acid found in blood.
Science Podcast
In this week's show: Detection of water on the Moon, environmental exposure and disease risk, advances in cancer immunotherapy, and more. Listen now.
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In this week's issue:
Editorial
An Education That Inspires
Bruce Alberts
http://www.sciencemag.org/cgi/content/summary/330/6003/427
Research Summaries
This Week in Science
Editor summaries of this week's papers.
http://www.sciencemag.org/content/vol330/issue6003/twis.dtl
Editors' Choice
Highlights of the recent literature
http://www.sciencemag.org/content/vol330/issue6003/twil.dtl
News of the Week
After Red Mud Flood, Scientists Try to Halt Wave of Fear and Rumors
Two weeks after caustic sludge—a byproduct of the aluminum industry whose pH can reach a dizzying 13—broke through a reservoir near Kolontár, Hungary, scientists say its environmental impact may be less severe than widely broadcast images suggested at first.
http://www.sciencemag.org/cgi/content/summary/330/6003/432
First Goldilocks Exoplanet May Not Exist
At a meeting last week in Turin, Italy, a group of exoplanet hunters announced that its observations show no sign of Gliese 581g, which only a couple of weeks earlier a rival group had announced was the long-sought Earth-like habitable planet.
http://www.sciencemag.org/cgi/content/summary/330/6003/433
How Wet the Moon? Just Damp Enough to Be Interesting
A series of reports of new water-related results from the moon beginning on page 463 of this week's issue of Science shows that the moon's recently discovered hydrosphere is nothing like Earth's watery regime, and many enigmas remain.
http://www.sciencemag.org/cgi/content/summary/330/6003/434
Rinderpest, Deadly for Cattle, Joins Smallpox as a Vanquished Disease
Rinderpest, an infectious disease that has decimated cattle and devastated their keepers for millennia, is gone. The United Nations Food and Agriculture Organization announced on 14 October in Rome that a 16-year eradication effort has succeeded and fieldwork has ended.
http://www.sciencemag.org/cgi/content/summary/330/6003/435
1.3 Billion Divided by 6.5 Million, and Watch That Floating Decimal
China's unique solution to getting a handle on a swelling migrant, or "floating," population in this year's census—adding presumed residents to an actual head count—unsettles some demographers.
http://www.sciencemag.org/cgi/content/summary/330/6003/436
From Science's Online Daily News Site
ScienceNOW reported this week that 2010 may be the worst year ever for coral death in the Caribbean, Iota Horologii boasts the shortest starspot cycle ever seen, the overall winner of the "Dance Your Ph.D." contest has been announced, and subtle differences in grammar can have a strong impact on people's perceptions, among other stories.
http://www.sciencemag.org/cgi/content/summary/330/6003/437
Iraq Banks on Peer Review to Rebuild Its Research Base
As part of an effort to build a research infrastructure, an Iraqi delegation visited the United States recently to study the U.S. system. Last week, Science spoke to two leaders of the delegation: Samir Raouf, Iraq's senior deputy minister for science and technology, and Hamid Ahmed, who advises the prime minister on education and higher education.
http://www.sciencemag.org/cgi/content/summary/330/6003/438
Reanalysis of French Cave Could Deal Setback to Neandertal Smarts
According to a study published online this week, new radiocarbon dating at a celebrated site in France indicates that jewelry and tools once attributed to Neandertals may be the work of modern humans.
http://www.sciencemag.org/cgi/content/summary/330/6003/439-a
From the Science Policy Blog
ScienceInsider reported this week that the presence of protesters last week at an agribiotech symposium at Huazhong Agricultural University led to an impromptu session between members of the general public and scientists that revealed the public's deep distrust of—and confusion about—genetically modified crops, among other stories.
http://www.sciencemag.org/cgi/content/summary/330/6003/439-b
Random Samples
http://www.sciencemag.org/content/vol330/issue6003/r-samples.dtl
News Focus
Immune Therapy Steps Up the Attack
After years of trying, cancer researchers say they are finally having success enlisting the body's own defenses to destroy tumors.
http://www.sciencemag.org/cgi/content/summary/330/6003/440
Radio Astronomers Take Arms Against a Sea of Signals
Beset by interference from telecommunications and radar, researchers are devising workarounds to preserve their view of the long-wavelength universe.
http://www.sciencemag.org/cgi/content/summary/330/6003/444
Letters
Who Pays the Price for Shared Social Responsibility?
http://www.sciencemag.org/cgi/content/full/330/6003/446-a
Who Pays the Price for Shared Social Responsibility?—Response
http://www.sciencemag.org/cgi/content/full/330/6003/446-b
Nuclear Waste: Thorium's Potential
http://www.sciencemag.org/cgi/content/full/330/6003/447
Nuclear Waste: Progress with Public Engagement
http://www.sciencemag.org/cgi/content/full/330/6003/448-a
Nuclear Waste: Progress with Public Engagement—Response
http://www.sciencemag.org/cgi/content/full/330/6003/448-b
Corrections and Clarifications
http://www.sciencemag.org/cgi/content/full/330/6003/448-c
Books et al.
A Naturalizer's Vision
Robert E. Kohler
This collection of essays samples Shapin's explorations of where, how, and by whom science has been produced.
http://www.sciencemag.org/cgi/content/summary/330/6003/450
The Agora of Knowledge
Manfred D. Laubichler
The exhibition's artifacts, installations, and media stations offer a variety of perspectives on the practice of science in Berlin over the past 300 years.
http://www.sciencemag.org/cgi/content/summary/330/6003/451-a
Books Received
A listing of books received at Science during the week ended 15 October 2010.
http://www.sciencemag.org/cgi/content/summary/330/6003/451-b
Policy Forum
Politics and Parthenotes
C. Tingen et al.
Broad restrictions on funding for human embryo research can stymie work that was unnecessarily precluded by a flawed U.S. law.
http://www.sciencemag.org/cgi/content/summary/330/6003/453
Perspectives
Flipping the Light Switch
N. Vogt and C. Desplan
A specific neuronal circuit controls how flies respond to light during development.
http://www.sciencemag.org/cgi/content/summary/330/6003/454
Creating Ligands with Multiple Personalities
Robert H. Crabtree
Ligands are being designed to respond to the solution environment and tune the reactivity of the transition metals to which they bind.
http://www.sciencemag.org/cgi/content/summary/330/6003/455
The Flu's Proton Escort
G. Fiorin et al.
A flurry of structural data provides sometimes conflicting insights into the M2 proton channel.
http://www.sciencemag.org/cgi/content/summary/330/6003/456
Chaos in the Gulf
Jean-Luc Thiffeault
Sophisticated mathematical analysis is providing insights into how the oil released in the Deepwater Horizon disaster is dispersing.
http://www.sciencemag.org/cgi/content/summary/330/6003/458
The Long-Term Benefits of Self-Rejection
S. I. Wright and S. C. H. Barrett
A trait that prevents self-fertilization in plants appears to promote evolutionary diversification.
http://www.sciencemag.org/cgi/content/summary/330/6003/459
Environment and Disease Risks
S. M. Rappaport and M. T. Smith
A new paradigm is needed to assess how a lifetime of exposure to environmental factors affects the risk of developing chronic diseases.
http://www.sciencemag.org/cgi/content/summary/330/6003/460
Brevia
Neutrino Spectroscopy Can Probe the Dark Matter Content in the Sun
I. Lopes and J. Silk
Dark matter in the center of the Sun would affect its internal structure and lead to a distinctive neutrino emission pattern.
http://www.sciencemag.org/cgi/content/abstract/330/6003/462
Research Articles
Detection of Water in the LCROSS Ejecta Plume
A. Colaprete et al.
A controlled spacecraft impact into a crater in the lunar south pole plunged through the lunar soil, revealing water and other volatiles.
http://www.sciencemag.org/cgi/content/abstract/330/6003/463
Reports
The LCROSS Cratering Experiment
P. H. Schultz et al.
A controlled spacecraft impact into a crater in the lunar south pole plunged through the lunar soil, revealing water and other volatiles.
http://www.sciencemag.org/cgi/content/abstract/330/6003/468
LRO-LAMP Observations of the LCROSS Impact Plume
G. R. Gladstone et al.
A controlled spacecraft impact into a crater in the lunar south pole plunged through the lunar soil, revealing water and other volatiles.
http://www.sciencemag.org/cgi/content/abstract/330/6003/472
Diviner Lunar Radiometer Observations of the LCROSS Impact
P. O. Hayne et al.
A controlled spacecraft impact into a crater in the lunar south pole plunged through the lunar soil, revealing water and other volatiles.
http://www.sciencemag.org/cgi/content/abstract/330/6003/477
Diviner Lunar Radiometer Observations of Cold Traps in the Moon’s South Polar Region
D. A. Paige et al.
A controlled spacecraft impact into a crater in the lunar south pole plunged through the lunar soil, revealing water and other volatiles.
http://www.sciencemag.org/cgi/content/abstract/330/6003/479
Hydrogen Mapping of the Lunar South Pole Using the LRO Neutron Detector Experiment LEND
I. G. Mitrofanov et al.
A controlled spacecraft impact into a crater in the lunar south pole plunged through the lunar soil, revealing water and other volatiles.
http://www.sciencemag.org/cgi/content/abstract/330/6003/483
A New Mixing Diagnostic and Gulf Oil Spill Movement
I. Mezic et al.
An ocean model can account for the trajectory and fragmentation of the recent Gulf of Mexico oil spill.
http://www.sciencemag.org/cgi/content/abstract/330/6003/486
Oscillatory Mass Transport in Vapor-Liquid-Solid Growth of Sapphire Nanowires
S. H. Oh et al.
High-resolution transmission electron microscopy is used to identify oscillatory growth of a sapphire nanowire.
http://www.sciencemag.org/cgi/content/abstract/330/6003/489
Species Selection Maintains Self-Incompatibility
E. E. Goldberg et al.
Self-incompatibility in a family of plants is associated with appreciably higher rates of speciation.
http://www.sciencemag.org/cgi/content/abstract/330/6003/493
Impeding Xist Expression from the Active X Chromosome Improves Mouse Somatic Cell Nuclear Transfer
K. Inoue et al.
Efficiency of mouse nuclear transfer was improved by correcting aberrant gene expression on the active X chromosome.
http://www.sciencemag.org/cgi/content/abstract/330/6003/496
Two Pairs of Neurons in the Central Brain Control Drosophila Innate Light Preference
Z. Gong et al.
A neural circuit connects perceptual inputs to behavioral outputs.
http://www.sciencemag.org/cgi/content/abstract/330/6003/499
Fast Vesicle Fusion in Living Cells Requires at Least Three SNARE Complexes
R. Mohrmann et al.
Membrane fusion proteins cooperate to promote rapid secretory vesicle exocytosis from neuroendocrine cells.
http://www.sciencemag.org/cgi/content/abstract/330/6003/502
Mechanisms of Proton Conduction and Gating in Influenza M2 Proton Channels from Solid-State NMR
F. Hu et al.
Histidine side-chain dynamics regulate proton conduction in an influenza proton channel.
http://www.sciencemag.org/cgi/content/abstract/330/6003/505
Insight into the Mechanism of the Influenza A Proton Channel from a Structure in a Lipid Bilayer
M. Sharma et al.
A tetrameric cluster of histidine and tryptophan residues, through its unique chemistry, shepherds protons through the M2 channel.
http://www.sciencemag.org/cgi/content/abstract/330/6003/509
Widespread Divergence Between Incipient Anopheles gambiae Species Revealed by Whole Genome Sequences
M. K. N. Lawniczak et al.
Gene flow among African malaria vectors is more restricted than previously thought.
http://www.sciencemag.org/cgi/content/abstract/330/6003/512
SNP Genotyping Defines Complex Gene-Flow Boundaries Among African Malaria Vector Mosquitoes
D. E. Neafsey et al.
Populations of African malaria vectors show signs of selective sweeps and ongoing speciation in their genomes.
http://www.sciencemag.org/cgi/content/abstract/330/6003/514
ATM Activation by Oxidative Stress
Z. Guo et al.
The protein kinase ATM is a sensor for reactive oxygen species.
http://www.sciencemag.org/cgi/content/abstract/330/6003/517
The Ligase PIAS1 Restricts Natural Regulatory T Cell Differentiation by Epigenetic Repression
B. Liu et al.
A ligase regulates repression of the Foxp3 promoter to restrict differentiation of natural regulatory T cells.
http://www.sciencemag.org/cgi/content/abstract/330/6003/521
Departments
New Products
A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.
http://www.sciencemag.org/cgi/content/summary/330/6003/526-a
Science Podcast
http://www.sciencemag.org/cgi/content/summary/330/6003/526-b
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