nature

THIS WEEK

Editorials

Mismeasure for mismeasure ▶

A critique of the work of Stephen Jay Gould should serve as encouragement to scrutinize the celebrated while they are still alive.

Damned if they do ▶

An industry approach to greener hydropower is far from perfect, but it does offer a way forwards.

Poetry in motion ▶

A quantitative approach to the humanities enriches research.

World View

Supreme Court ruling is good, bad and ugly ▶

Monday's key US legal decision on emissions regulation was influenced by the unjustified attacks on climate science, says Douglas Kysar.

Seven Days

Seven days: 17-23 June 2011 ▶

The week in science

NEWS IN FOCUS

Vaccine trial's ethics criticized ▶

Collapsed trial fuels unfounded vaccine fears.

Open access comes of age ▶

Publishing model enters phase of slower but steady growth.

City living marks the brain ▶

Neuroscientists study social risk factor for mental illness.

Worth a dam? ▶

Voluntary agreement enables rating of hydroelectric impacts.

Researchers tweet technical talk ▶

In the latest trend in scientific discourse, journal clubs and data disclosures move to Twitter.

Drug buddies ▶

The pharmaceutical industry is seeking stronger ties with academia in a bid to speed up drug development.

Feature

Culturomics: Word play ▶

By mining a database of the world's books, Erez Lieberman Aiden is attempting to automate much of humanities research. But is the field ready to be digitized?

COMMENT

Hidden depths ▶

A staggering lack of undersea data hampers our understanding of earthquakes and tsunamis. Geophysicists must put more instruments offshore, says Andrew V. Newman.

US and China need contact, not cold war ▶

Attempts to isolate the Chinese space community undermine US interests, says Gregory Kulacki.

Books and Arts

Psychology: How we form beliefs ▶

Religions and superstitions may stem from the brain's ability to spot patterns and intent, finds A. C. Grayling.

Books in brief ▶

Demographics: The growth of nations ▶

Michael Sargent enjoys a social history of how height and lifespan increased during the Industrial Revolution.

Art: Treasures fit for a prince ▶

A Monaco exhibition showcases the marvels of the city-state's oceanic museum, discovers Alison Abbott.

Correspondence

Don't base Spanish funding on citations Alonso Rodríguez-Navarro | Is China producing too many PhDs? Zhu Liu & Yong Geng | Reward research that informs policy Ryan Meyer & Peat Leith | Promoting science careers in Brazil Lucas Leite Cunha & Laura Sterian Ward | Community is key to REDD success Brian Weeks & Christopher Filardi

Corrections

Correction: Egypt invests in science ▶

RESEARCH

Latest Online

Structure of the human histamine H₁ receptor complex with doxepin ▶

Tatsuro Shimamura, Mitsunori Shiroishi, Simone Weyand, Hirokazu Tsujimoto, Graeme Winter et al.

The biogenic amine histamine is an important pharmacological mediator involved i...

Tracking apex marine predator movements in a dynamic ocean ▶

B. A. Block, I. D. Jonsen, S. J. Jorgensen, A. J. Winship, S. A. Shaffer et al.

Pelagic marine predators face unprecedented challenges and uncertain futures. Ov...

XUTs are a class of Xrn1-sensitive antisense regulatory non-coding RNA in yeast ▶

E. L. van Dijk, C. L. Chen, Y. d’Aubenton-Carafa, S. Gourvennec, M. Kwapisz et al.

Non-coding (nc)RNAs are key players in numerous biological processes such as gen...

Intravenous gammaglobulin suppresses inflammation through a novel T_H2 pathway ▶

Robert M. Anthony, Toshihiko Kobayashi, Fredrik Wermeling & Jeffrey V. Ravetch

High-dose intravenous immunoglobulin is a widely used therapeutic preparation of...

A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter ▶

Diego De Stefani, Anna Raffaello, Enrico Teardo, Ildikò Szabò & Rosario Rizzuto

Mitochondrial Ca2+ homeostasis has a key role in the regulation of aerobic metab...

Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter ▶

Joshua M. Baughman, Fabiana Perocchi, Hany S. Girgis, Molly Plovanich, Casey A. Belcher-Timme et al.

Mitochondria from diverse organisms are capable of transporting large amounts of...

Articles and Letters

Regioselective reactions for programmable resveratrol oligomer synthesis ▶

Scott A. Snyder, Andreas Gollner & Maria I. Chiriac

Although much attention has been devoted to resveratrol, a unique polyphenol pro...

Structural basis of steroid hormone perception by the receptor kinase BRI1 ▶

Michael Hothorn, Youssef Belkhadir, Marlene Dreux, Tsegaye Dabi, Joseph. P. Noel et al.

Polyhydroxylated steroids are regulators of body shape and size in higher organi...

Structural insight into brassinosteroid perception by BRI1 ▶

Ji She, Zhifu Han, Tae-Wuk Kim, Jinjing Wang, Wei Cheng et al.

Brassinosteroids are essential phytohormones that have crucial roles in plant gr...

Condensin association with histone H2A shapes mitotic chromosomes ▶

Kenji Tada, Hiroaki Susumu, Takeshi Sakuno & Yoshinori Watanabe

Chromosome structure is dynamically regulated during cell division, and this reg...

Flying in a flock comes at a cost in pigeons ▶

James R. Usherwood, Marinos Stavrou, John C. Lowe, Kyle Roskilly & Alan M. Wilson

Flying birds often form flocks, with social, navigational and anti-predator impl...

City living and urban upbringing affect neural social stress processing in humans ▶

Florian Lederbogen, Peter Kirsch, Leila Haddad, Fabian Streit, Heike Tost et al.

More than half of the world’s population now lives in cities, making the...

Non-adaptive origins of interactome complexity ▶

Ariel Fernández & Michael Lynch

The boundaries between prokaryotes, unicellular eukaryotes and multicellular euk...

A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects ▶

Jae Man Lee, Yoon Kwang Lee, Jennifer L. Mamrosh, Scott A. Busby, Patrick R. Griffin et al.

Nuclear hormone receptors regulate diverse metabolic pathways and the orphan nuc...

Regulation of angiogenesis by a non-canonical Wnt–Flt1 pathway in myeloid cells ▶

James A. Stefater III, Ian Lewkowich, Sujata Rao, Giovanni Mariggi, April C. Carpenter et al.

Myeloid cells are a feature of most tissues. Here we show that during developmen...

Determinants of nucleosome organization in primary human cells ▶

Anton Valouev, Steven M. Johnson, Scott D. Boyd, Cheryl L. Smith, Andrew Z. Fire et al.

Nucleosomes are the basic packaging units of chromatin, modulating accessibility...

Agonist-bound adenosine A_2A receptor structures reveal common features of GPCR activation ▶

Guillaume Lebon, Tony Warne, Patricia C. Edwards, Kirstie Bennett, Christopher J. Langmead et al.

Adenosine receptors and β-adrenoceptors are G-protein-coupled receptors (G...

Tunable pK_a values and the basis of opposite charge selectivities in nicotinic-type receptors ▶

Gisela D. Cymes & Claudio Grosman

Among ion channels, only the nicotinic-receptor superfamily has evolved to gener...

News & Views

Social neuroscience: Stress and the city ▶

Daniel P. Kennedy & Ralph Adolphs

Metabolism: A lipid for fat disorders ▶

Holly A. Ingraham

Aerodynamics: The cost of flight in flocks ▶

Geoffrey Spedding

Research Highlights

Phylogenetics: Picking out the pika's origins | Molecular psychology: Cellular cues to compulsive eating | Cancer biology: Senescence not so harmless | Evolution: Male harassment can doom species | Cellular biology: A microscopist's litmus test | Cancer biology: When push comes to shove in cancer | Ocean chemistry: Cushion against acidification | Physiology and climate: Air conditioning all in the nose | Brain and behaviour: The voter's grey matter

NEWS & COMMENT

Mismeasure for mismeasure | Psychology: How we form beliefs | Books in brief | Demographics: The growth of nations | Promoting science careers in Brazil Lucas Leite Cunha & Laura Sterian Ward

CAREERS

Renewable energy: Making fuels for the future

More Biological Sciences ▶

RESEARCH

Latest Online

Structure of the human histamine H₁ receptor complex with doxepin ▶

Tatsuro Shimamura, Mitsunori Shiroishi, Simone Weyand, Hirokazu Tsujimoto, Graeme Winter et al.

The biogenic amine histamine is an important pharmacological mediator involved i...

Articles and Letters

Regioselective reactions for programmable resveratrol oligomer synthesis ▶

Scott A. Snyder, Andreas Gollner & Maria I. Chiriac

Although much attention has been devoted to resveratrol, a unique polyphenol pro...

Agonist-bound adenosine A_2A receptor structures reveal common features of GPCR activation ▶

Guillaume Lebon, Tony Warne, Patricia C. Edwards, Kirstie Bennett, Christopher J. Langmead et al.

Adenosine receptors and β-adrenoceptors are G-protein-coupled receptors (G...

Tunable pK_a values and the basis of opposite charge selectivities in nicotinic-type receptors ▶

Gisela D. Cymes & Claudio Grosman

Among ion channels, only the nicotinic-receptor superfamily has evolved to gener...

News & Views

Organic chemistry: Triumph for unnatural synthesis ▶

Stéphane Quideau

Research Highlights

Ocean chemistry: Cushion against acidification

CAREERS

Renewable energy: Making fuels for the future

More Chemical Sciences ▶

RESEARCH

Latest Online

A salt-water reservoir as the source of a compositionally stratified plume on Enceladus ▶

F. Postberg, J. Schmidt, J. Hillier, S. Kempf & R. Srama

The discovery of a plume of water vapour and ice particles emerging from warm fr...

Articles and Letters

X-ray illumination of the ejecta of supernova 1987A ▶

J. Larsson, C. Fransson, G. Östlin, P. Gröningsson, A. Jerkstrand et al.

When a massive star explodes as a supernova, substantial amounts of radioactive ...

Hydrogen-poor superluminous stellar explosions ▶

R. M. Quimby, S. R. Kulkarni, M. M. Kasliwal, A. Gal-Yam, I. Arcavi et al.

Supernovae are stellar explosions driven by gravitational or thermonuclear energ...

Experimental non-classicality of an indivisible quantum system ▶

Radek Lapkiewicz, Peizhe Li, Christoph Schaeff, Nathan K. Langford, Sven Ramelow et al.

In contrast to classical physics, quantum theory demands that not all properties...

News & Views

Materials science: Graphene moiré mystery solved? ▶

Allan H. MacDonald & Rafi Bistritzer

Quantum physics: Correlations without parts ▶

Adán Cabello

Research Highlights

Astronomy: Blaze marks star's violent death

NEWS & COMMENT

Poetry in motion | Books in brief | Reward research that informs policy Ryan Meyer & Peat Leith

More Physical Sciences ▶

RESEARCH

Latest Online

Tracking apex marine predator movements in a dynamic ocean ▶

B. A. Block, I. D. Jonsen, S. J. Jorgensen, A. J. Winship, S. A. Shaffer et al.

Pelagic marine predators face unprecedented challenges and uncertain futures. Ov...

A salt-water reservoir as the source of a compositionally stratified plume on Enceladus ▶

F. Postberg, J. Schmidt, J. Hillier, S. Kempf & R. Srama

The discovery of a plume of water vapour and ice particles emerging from warm fr...

Articles and Letters

City living and urban upbringing affect neural social stress processing in humans ▶

Florian Lederbogen, Peter Kirsch, Leila Haddad, Fabian Streit, Heike Tost et al.

More than half of the world’s population now lives in cities, making the...

News & Views

Social neuroscience: Stress and the city ▶

Daniel P. Kennedy & Ralph Adolphs

NEWS & COMMENT

Damned if they do | Hidden depths | Art: Treasures fit for a prince | Reward research that informs policy Ryan Meyer & Peat Leith | Community is key to REDD success Brian Weeks & Christopher Filardi

More Earth & Environmental Sciences ▶

Biofuels ▶

Introduction: Next generation biofuels ▶

Proponents of biomass-based fuels push for sustainability against a steady tide of conflicting analysis, but can advanced biofuels cut the mustard? 

Agriculture: Beyond food versus fuel ▶

The most controversial aspect of biofuels is the perceived competition for farmland. Will advances in biofuels and agriculture send this trade-off speeding towards the history books? 

Fuel options: The ideal biofuel ▶

A biomass-based fuel needs to be cheap and energy dense. Gasoline sets a high standard. 

Lignocellulose: A chewy problem ▶

The inedible parts of plants are feeding the next generation of biofuels. But extracting the energy-containing molecules is a challenging task. 

Algae: The scum solution ▶

The green slime that covers ponds is an efficient factory for turning sunlight into fuel, but growing it on an industrial scale will take ingenuity. 

Perspective: Don't foul the water ▶

Shifting from corn to perennial crops in making biofuels is essential to save clean water, argues Jeremy Martin 

Local benefits: The seeds of an economy ▶

Biofuels could help poor nations modernize, but scaling up aid supported projects to commercial operations is far from easy. 

Perspective: A new hope for Africa ▶

Bioenergy could help bring food security to the world's poorest continent, say Lee R. Lynd and Jeremy Woods. 

Policy: Fuelling politics ▶

Biofuels have been hailed as key to reducing our fossil-fuel dependence, yet their environmental and social impacts remain uncertain. A complex task lies ahead for policy makers. 

Perspective: Lessons from Brazil ▶

Thirty five years of experience has taught one of the world's leading biofuels producers several essential lessons, which other countries should heed, says Marcia Moraes. 

Sponsors

The termite hunters ▶

Renewable energy: Making fuels for the future ▶

The field of biofuels has suffered from cycles of interest and neglect. Still, enterprising researchers have myriad options.

Oh, Canada... ▶

A tax-law change has dealt a heavy blow to Canadian postdocs, argues Lucie Low

Careers related news & comment

Worth a dam? | Drug buddies | Don't base Spanish funding on citations Alonso Rodríguez-Navarro | Is China producing too many PhDs? Zhu Liu & Yong Geng | Reward research that informs policy Ryan Meyer & Peat Leith | Promoting science careers in Brazil Lucas Leite Cunha & Laura Sterian Ward | Community is key to REDD success Brian Weeks & Christopher Filardi

Postdoctoral Research Fellow in Biochemical Analysis of the Smc5 / 6 Complex

UNIVERSITY OF SUSSEX Brighton, Sussex, United Kingdom

Assistant Professor, Microbiology. Tenure-track.

Department of Biology, The University of Texas at Tyler Tyler, TX

Lecturer in Experimental Chemistry (x2)

UCL Department of Chemistry London, United Kingdom

Postdoctoral Research Assistant

University of Reading Reading, United Kingdom

Assistant Professor, Microbiology. Tenure-track.

Department of Biology, The University of Texas at Tyler Tyler, TX

Physiology and Biophysics of Photosynthetic Organisms

21.-28.08.11 Frankfurt am Main, Germany