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Science Table of Contents Text for 12 October 2012
[2012-10-12]

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The New BD FACSJazz™ Cell Sorter
Perfectly tuned cell sorting is now available with the new BD FACSJazz. Built on a proven, dependable platform, it may change the way you'll think of cell sorting with ease of operation, affordability, and a benchtop fit. Exceedingly capable performance whether as a soloist or part of your core lab ensemble. bdbiosciences.com/jazz


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[About the cover]

Science, 12 October 2012 (Volume 338, Issue 6104)
http://www.sciencemag.org/content/vol338/issue6104/index.dtl?etoc

Also online at Science::




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In this week's issue:


Research Summaries


This Week in Science
Editor summaries of this week papers.
http://www.sciencemag.org/content/vol338/issue6104/twis.dtl

Editors' Choice
Highlights of the recent literature.
http://www.sciencemag.org/content/vol338/issue6104/twil.dtl


Editorial

Enabling Scientific Innovation
James S. Langer
http://www.sciencemag.org/cgi/content/summary/338/6104/171


News of the Week

This Week's Section

http://www.sciencemag.org/cgi/content/summary/338/6104/176-a

Around the World

In science news around the world this week, the Australian Square Kilometre Array Pathfinder, which comprises 36 12-meter-diameter antennas, was completed last week in Western Australia; an expert panel has dismissed as "inconclusive" a controversial study claiming to find that rats fed genetically modified maize developed tumors at a higher rate than control animals; and disgraced Dutch psychologist Diederik Stapel is under investigation by Dutch prosecutors.
http://www.sciencemag.org/cgi/content/summary/338/6104/176-b

Random Sample

Schools in England are failing girls who want to study physics; the Royal Society in London will hold an "edit-a-thon" event on 19 October in which Wikipedia articles on illustrious yet unsung female scientists will be expanded or created; and microscopic analysis of Pegomastax teeth suggest that heterodontosaurs used their fangs to nip and spar.
http://www.sciencemag.org/cgi/content/summary/338/6104/176-c

Newsmakers

This week's Newsmakers are Terry Plank, a geochemist at Columbia University who studies the intersection of hydrology and volcanology, and the other winners of the MacArthur Fellowships.
http://www.sciencemag.org/cgi/content/summary/338/6104/176-d

Findings
http://www.sciencemag.org/content/vol338/issue6104/findings.dtl


News & Analysis

Reprogrammed Cells Earn Biologists Top Honor
Gretchen Vogel et al.
Work upending the assumption that a cell's differentiation and maturation could not be reversed netted John Gurdon and Shinya Yamanaka this year's Nobel Prize in physiology or medicine.
http://www.sciencemag.org/cgi/content/summary/338/6104/178

Manipulators of the Quantum Realm Lauded
Adrian Cho
This year's Nobel Prize in physics honors Serge Haroche and David Wineland for creating delicate quantum states of individual particles and doing novel things with them.
http://www.sciencemag.org/cgi/content/summary/338/6104/179

Oh, Baby: Fight Brews Over U.S. Import of Beluga Whales
Emily Underwood
The Georgia Aquarium's controversial request to import 18 wild beluga whales captured in the Sea of Okhotsk for display and breeding is expected to get its first formal airing on 12 October.
http://www.sciencemag.org/cgi/content/summary/338/6104/180

NIH Funding Shifts With Disease Lobbying, Study Suggests
Jocelyn Kaiser
The growing power and influence of disease lobbying groups over the past 2 decades have dramatically reshaped the priorities of the U.S. National Institutes of Health, according to a new analysis.
http://www.sciencemag.org/cgi/content/summary/338/6104/181

New Arctic Research Vessel Ready to Make a Splash
Carolyn Gramling
Polar researchers will soon have their own ride to the icy waters of the Bering Sea and points north: the Sikuliaq, a $200 million, nearly 80-meter ship owned by the U.S. National Science Foundation.
http://www.sciencemag.org/cgi/content/summary/338/6104/183


News Focus

Aftershocks in the Courtroom
Edwin Cartlidge
An Italian judge will soon decide whether 30 people died because seven experts downplayed the risk of a major earthquake in L'Aquila in 2009.
http://www.sciencemag.org/cgi/content/summary/338/6104/184

The Seven Defendants

http://www.sciencemag.org/cgi/content/summary/338/6104/185

Turning Back the Clock: Slowing the Pace of Prehistory
Ann Gibbons
New work suggests that mutations arise more slowly in humans than previously thought, raising questions about the timetable of evolutionary events.
http://www.sciencemag.org/cgi/content/summary/338/6104/189


Letters

Baits, Budget Cuts: A Deadly Mix
Antoni Margalida
http://www.sciencemag.org/cgi/content/summary/338/6104/192-a

Saving Vietnam's Wildlife Through Social Media
L. T. P. Nghiem et al.
http://www.sciencemag.org/cgi/content/summary/338/6104/192-b

Making Science Education Relevant
William A. Wulf
http://www.sciencemag.org/cgi/content/summary/338/6104/193-a

Corrections and Clarifications

http://www.sciencemag.org/cgi/content/summary/338/6104/193-b


Technical Comments

Comment on "Climatic Niche Shifts Are Rare Among Terrestrial Plant Invaders"
Bruce L. Webber et al.
http://www.sciencemag.org/cgi/content/summary/338/6104/193-c

Response to Comment on "Climatic Niche Shifts Are Rare Among Terrestrial Plant Invaders"
Antoine Guisan et al.
http://www.sciencemag.org/cgi/content/summary/338/6104/193-d


Books et al.

Heterodoxy and Its Discontents
Alex Wellerstein
Through an examination of the controversies sparked by best-selling author Immanuel Velikovsky (Worlds in Collision), Gordin considers the shifting location of the boundaries of legitimate science.
http://www.sciencemag.org/cgi/content/summary/338/6104/194

To Endow Trust
Benedikt Herrmann
Synthesizing anthropology and biogeography, Harcourt discusses how geography has affected our anatomy, physiology, cultures, and population densities.
http://www.sciencemag.org/cgi/content/summary/338/6104/195-a

Books Received

A listing of books received at Science during the week ending 05 October 2012.
http://www.sciencemag.org/cgi/content/summary/338/6104/195-b


Policy Forum

Standards and Infrastructure for Innovation Data Exchange
Laurel L. Haak et al.
Data on the global R&D enterprise are inconsistently structured and shared, which hinders understanding and policy.
http://www.sciencemag.org/cgi/content/summary/338/6104/196


Perspectives

Animal Behavior and the Microbiome
Vanessa O. Ezenwa et al.
Feedbacks between microbiomes and their hosts affect a range of animal behaviors.
http://www.sciencemag.org/cgi/content/summary/338/6104/198

Putting the Squeeze on Phototransduction
Emily R. Liman
Changes in the physical properties of the lipid bilayer stimulate the opening of ion channels during fly phototransduction.
http://www.sciencemag.org/cgi/content/summary/338/6104/200

Physical Biology Returns to Morphogenesis
Ray Keller
Understanding how cells coordinately shape an organism is grounded in a history of biophysical analyses of the molecules, mechanics, and forces that govern cell movements.
http://www.sciencemag.org/cgi/content/summary/338/6104/201

A Golden Spike for Planetary Science
Richard P. Binzel
The progression from astronomical observation to geochemical analysis epitomizes advancements in planetary exploration.
http://www.sciencemag.org/cgi/content/summary/338/6104/203

Downsizing the Deep Biosphere
Kai-Uwe Hinrichs et al.
A recent study provides new constraints on the size and distribution of microbial biomass beneath the ocean floor, but key factors remain uncertain.
http://www.sciencemag.org/cgi/content/summary/338/6104/204

Cilia Discern Left from Right
Dominic P. Norris et al.
Determination of vertebrate left-right body asymmetry requires immotile cilia that sense fluid flow generated by nearby motile cilia.
http://www.sciencemag.org/cgi/content/summary/338/6104/206

Seeing Is Believing
Benjamin A. Brooks
Satellite data and computational modeling provide evidence for a spheroidal magma body rising within the crust below the Altiplano Plateau in the central Andes.
http://www.sciencemag.org/cgi/content/summary/338/6104/207


Introduction to Special Issue

Forceful Thinking
Beverly A. Purnell
http://www.sciencemag.org/cgi/content/summary/338/6104/209


Reviews

Developmental Pattern Formation: Insights from Physics and Biology
Anna Kicheva et al.
http://www.sciencemag.org/cgi/content/summary/338/6104/210

Knowing the Boundaries: Extending the Differential Adhesion Hypothesis in Embryonic Cell Sorting
Jeffrey D. Amack et al.
http://www.sciencemag.org/cgi/content/summary/338/6104/212


Perspectives

A Dynamical-Systems View of Stem Cell Biology
Chikara Furusawa et al.
http://www.sciencemag.org/cgi/content/summary/338/6104/215

Physico-Genetic Determinants in the Evolution of Development
Stuart A. Newman
http://www.sciencemag.org/cgi/content/summary/338/6104/217


Brevia

Genome Sequencing Identifies a Basis for Everolimus Sensitivity
Gopa Iyer et al.
Tumor genome sequencing reveals the molecular basis of a patient's unexpected and dramatic response to a cancer drug.
http://www.sciencemag.org/cgi/content/summary/338/6104/221


Research Articles

A High-Coverage Genome Sequence from an Archaic Denisovan Individual
Matthias Meyer et al.
A close-up look provides clues to the relationships between modern humans, Denisovans, and Neandertals.
http://www.sciencemag.org/cgi/content/summary/338/6104/222

Cilia at the Node of Mouse Embryos Sense Fluid Flow for Left-Right Determination via Pkd2
Satoko Yoshiba et al.
A Ca2+ channel implicated in polycystic kidney disease helps to establish the left-right body axis of the mammalian embryo.
http://www.sciencemag.org/cgi/content/summary/338/6104/226


Reports

Strain Tuning of Individual Atomic Tunneling Systems Detected by a Superconducting Qubit
Grigorij J. Grabovskij et al.
A process responsible for the decoherence of superconducting qubits is controlled using mechanical strain.
http://www.sciencemag.org/cgi/content/summary/338/6104/232

Observation of Resonances in Penning Ionization Reactions at Sub-Kelvin Temperatures in Merged Beams
A. B. Henson et al.
Minimizing the relative velocity spread among reaction partners in a supersonic beam reveals nonclassical dynamics.
http://www.sciencemag.org/cgi/content/summary/338/6104/234

An Ancient Core Dynamo in Asteroid Vesta
Roger R. Fu et al.
Paleomagnetic studies of a meteorite from asteroid Vesta reveal remanent magnetization produced by an ancient core dynamo.
http://www.sciencemag.org/cgi/content/summary/338/6104/238

Elemental Mapping by Dawn Reveals Exogenic H in Vesta's Regolith
Thomas H. Prettyman et al.
Analysis of data from the Dawn spacecraft implies that asteroid Vesta is rich in volatiles.
http://www.sciencemag.org/cgi/content/summary/338/6104/242

Pitted Terrain on Vesta and Implications for the Presence of Volatiles
B. W. Denevi et al.
Analysis of data from the Dawn spacecraft implies that asteroid Vesta is rich in volatiles.
http://www.sciencemag.org/cgi/content/summary/338/6104/246

Sombrero Uplift Above the Altiplano-Puna Magma Body: Evidence of a Ballooning Mid-Crustal Diapir
Yuri Fialko et al.
Subsidence accompanies uplift below a massive rising magma body in the central Andes mountains.
http://www.sciencemag.org/cgi/content/summary/338/6104/250

Adhesion Functions in Cell Sorting by Mechanically Coupling the Cortices of Adhering Cells
Jean-Leon Maître et al.
Cell adhesion provides a mechanical scaffold for cell cortex tension to drive cell sorting during zebrafish gastrulation.
http://www.sciencemag.org/cgi/content/summary/338/6104/253

Forces Driving Epithelial Spreading in Zebrafish Gastrulation
Martin Behrndt et al.
Contraction of an actomyosin ring drives epithelial morphogenesis during embryonic development.
http://www.sciencemag.org/cgi/content/summary/338/6104/257

Photomechanical Responses in Drosophila Photoreceptors
Roger C. Hardie et al.
Light sensing involves contraction of the photoreceptor cell membrane physically gating the light-sensitive channels.
http://www.sciencemag.org/cgi/content/summary/338/6104/260

Bacterial Quorum Sensing and Metabolic Incentives to Cooperate
Ajai A. Dandekar et al.
Cooperating groups of bacteria resist infiltration by noncooperating cheats by co-regulating shared and individual products.
http://www.sciencemag.org/cgi/content/summary/338/6104/264

Quantifying the Impact of Human Mobility on Malaria
Amy Wesolowski et al.
Geographical information in mobile phone records for 15 million Kenyans is linked to malaria prevalence estimates.
http://www.sciencemag.org/cgi/content/summary/338/6104/267

Preference by Association: How Memory Mechanisms in the Hippocampus Bias Decisions
G. Elliott Wimmer et al.
Remembered links between objects can result in the unintentional linking of their values and can affect choices.
http://www.sciencemag.org/cgi/content/summary/338/6104/270


Products & Materials

New Products

A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.
http://www.sciencemag.org/cgi/content/summary/338/6104/274-a


Podcast

Science Podcast

The show includes the evolution of development, the human mutation rate, publishing patterns, and more.
http://www.sciencemag.org/cgi/content/summary/338/6104/274-b


From the AAAS Office of Publishing and Member Services

New Developments in Science and Technology - 60th Anniversary Special Issue, Beihang University (BUAA)

http://www.sciencemag.org/cgi/content/summary/338/6104/274-c

AAAS
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- - - - - Sponsored by BD Biosciences - - - - -


The New BD FACSJazz™ Cell Sorter
Perfectly tuned cell sorting is now available with the new BD FACSJazz. Built on a proven, dependable platform, it may change the way you'll think of cell sorting with ease of operation, affordability, and a benchtop fit. Exceedingly capable performance whether as a soloist or part of your core lab ensemble. bdbiosciences.com/jazz



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