nature alert

Animal rights and wrongs ▶

A Nature survey shows the pernicious impact of activism on biomedical scientists. More institutions must offer researchers the training they need to stand up for their work. Read Editorial ▶

On the rebound ▶

A critical report has fuelled arguments about the benefits of energy efficiency. Read Editorial ▶

Rights for all ▶

Scientists should push for fair treatment of Turkish academics arrested on little evidence. Read Editorial ▶

Unpublished results hide the decline effect ▶

Some effects diminish when tests are repeated. Jonathan Schooler says being open about findings that don't make the scientific record could reveal why. Read Column ▶

Seven days: 24 February 2011 ▶

The week in science Read Seven Days ▶

Clash over Iran's capability ▶

Effects of sanctions and computer worm on uranium production are disputed. Read News ▶

Marine biology network launches into choppy waters ▶

Ambitious European project hopes to navigate uncertain funding future. Read News ▶

Faculty members in conflict with president of Japanese university ▶

Allegations over research results highlight the difficulties of investigating high-ranking administrators. Read News ▶

Genzyme deal set to alter biotech landscape ▶

Maintaining innovative culture will be a key challenge for new owners of industry stalwart. Read News ▶

Europe's innovation hub finally KICs off ▶

Large networks of researchers and companies aim to develop and commercialize marketable products. Read News ▶

Climate strife and political life ▶

Joe Aldy, former adviser to Barack Obama for energy and environment, assesses the state of US climate legislation. Read News ▶

Animal research: Battle scars ▶

Nearly one-quarter of biologists say they have been affected by animal activists. A Nature poll exposes the Battle Scars Read Feature ▶

Animal Research: The radical ▶

Researcher by day and activist by night, Joseph Harris was leading an untenable double life that eventually landed him in prison. Read Feature ▶

Animal testing: TV or not TV? ▶

Two views on whether scientists who believe that animal experimentation is necessary should become public advocates, or work quietly behind the scenes. Read Comment ▶

Earth systems: Shaped by life ▶

Wolfgang Lucht sees a lesson for humanity's future in the long co-evolution of our planet and its inhabitants. Read Books and Arts ▶

Books in brief ▶

Read Books and Arts ▶

History: Science and sensibility ▶

Mechanical world views were replaced by more sensory beliefs after the rise of the novel, finds George Rousseau. Read Books and Arts ▶

Chemistry: Enigmatic elements ▶

A Philadelphia exhibition is a playful celebration of the periodic table, reports Katharine Sanderson. Read Books and Arts ▶

Q&A: Perfumes preserved ▶

Roman Kaiser, a chemist at the Givaudan Research Centre in Dübendorf, Switzerland, has recreated the scents of hundreds of rare and endangered plants in his laboratory, some of which he describes in his latest book. Here he explains how he preserves the smell of disappearing flora. Read Books and Arts ▶

Differing opinion, not misconduct ▶

Steven B. Abramson Read Correspondence ▶

Stuttering studies support treatment ▶

Mark Onslow, Ann Packman & Peter Howell Read Correspondence ▶

Clarifying relatives and ancestors ▶

Walter Shearer Read Correspondence ▶

Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor ▶

Kerry J. Ressler, Kristina B. Mercer, Bekh Bradley, Tanja Jovanovic, Amy Mahan et al.

Pituitary adenylate cyclase-activating polypeptide (PACAP) is known to broadly r... Read Research ▶

Transient Hoogsteen base pairs in canonical duplex DNA ▶

Evgenia N. Nikolova, Eunae Kim, Abigail A. Wise, Patrick J. O’Brien, Ioan Andricioaei et al.

Sequence-directed variations in the canonical DNA double helix structure that re... Read Research ▶

Intrinsic transition of embryonic stem-cell differentiation into neural progenitors ▶

Daisuke Kamiya, Satoe Banno, Noriaki Sasai, Masatoshi Ohgushi, Hidehiko Inomata et al.

The neural fate is generally considered to be the intrinsic direction of embryon... Read Research ▶

An armoured Cambrian lobopodian from China with arthropod-like appendages ▶

Jianni Liu, Michael Steiner, Jason A. Dunlop, Helmut Keupp, Degan Shu et al.

Cambrian fossil Lagerstätten preserving soft-bodied organisms have contri... Read Research ▶

Consequences of climate change on the tree of life in Europe ▶

Wilfried Thuiller, Sébastien Lavergne, Cristina Roquet, Isabelle Boulangeat, Bruno Lafourcade et al.

Many species are projected to become vulnerable to twenty-first-century climate ... Read Research ▶

Synaptic potentiation onto habenula neurons in the learned helplessness model of depression ▶

Bo Li, Joaquin Piriz, Martine Mirrione, ChiHye Chung, Christophe D. Proulx et al.

The cellular basis of depressive disorders is poorly understood. Recent studies ... Read Research ▶

Prion propagation and toxicity in vivo occur in two distinct mechanistic phases ▶

Malin K. Sandberg, Huda Al-Doujaily, Bernadette Sharps, Anthony R. Clarke & John Collinge

Mammalian prions cause fatal neurodegenerative conditions including Creutzfeldt|... Read Research ▶

Programming the magnitude and persistence of antibody responses with innate immunity ▶

Sudhir Pai Kasturi, Ioanna Skountzou, Randy A. Albrecht, Dimitrios Koutsonanos, Tang Hua et al.

Many successful vaccines induce persistent antibody responses that can last a li... Read Research ▶

Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL–RANK signalling ▶

Wei Tan, Weizhou Zhang, Amy Strasner, Sergei Grivennikov, Jin Q. Cheng et al.

Inflammatory mechanisms influence tumorigenesis and metastatic progression even ... Read Research ▶

Co-directional replication–transcription conflicts lead to replication restart ▶

Houra Merrikh, Cristina Machón, William H. Grainger, Alan D. Grossman & Panos Soultanas

Head-on encounters between the replication and transcription machineries on the ... Read Research ▶

Crystal structure of the CusBA heavy-metal efflux complex of Escherichia coli  ▶

Chih-Chia Su, Feng Long, Michael T. Zimmermann, Kanagalaghatta R. Rajashankar, Robert L. Jernigan et al.

Gram-negative bacteria, such as Escherichia coli, expel toxic chemicals through ... Read Research ▶

Structural basis of RNA polymerase II backtracking, arrest and reactivation ▶

Alan C. M. Cheung & Patrick Cramer

During gene transcription, RNA polymerase (Pol) II moves forwards along DNA and ... Read Research ▶

Fat cells reactivate quiescent neuroblasts via TOR and glial insulin relays in Drosophila  ▶

Rita Sousa-Nunes, Lih Ling Yee & Alex P. Gould

Many stem, progenitor and cancer cells undergo periods of mitotic quiescence fro... Read Research ▶

Recapitulation of premature ageing with iPSCs from Hutchinson–Gilford progeria syndrome ▶

Guang-Hui Liu, Basam Z. Barkho, Sergio Ruiz, Dinh Diep, Jing Qu et al.

Hutchinson–Gilford progeria syndrome (HGPS) is a rare and fatal human pr... Read Research ▶

Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia ▶

Vladimir Vacic, Shane McCarthy, Dheeraj Malhotra, Fiona Murray, Hsun-Hua Chou et al.

Rare copy number variants (CNVs) have a prominent role in the aetiology of schiz... Read Research ▶

Psychiatry: A molecular shield from trauma ▶

Murray B. Stein

Why do some people develop post-traumatic stress disorder, but others emerge fro... Read Research ▶

Spectroscopy: Unexpected interactions ▶

Ivano Bertini & Claudio Luchinat

Unpaired electrons can exert effects that allow interatomic contacts in molecule... Read Research ▶

Prion diseases: Infectivity versus toxicity ▶

Reed B. Wickner

Prions are infectious proteins that can cause deadly diseases in mammals. Detail... Read Research ▶

Biophysics: Flipping Watson and Crick ▶

Barry Honig & Remo Rohs

Watson–Crick base pairs underpin the DNA double helix. Evidence of trans... Read Research ▶

Cancer: When catastrophe strikes a cell ▶

Jose M. C. Tubio & Xavier Estivill

In 2–3% of cancers, a single genetic event may have led to hund... Read Research ▶

Climate change and evolutionary adaptation ▶

Ary A. Hoffmann & Carla M. Sgrò

Evolutionary adaptation can be rapid and potentially help species counter stress... Read Research ▶

Zoology: Fighters egged on by pheromones ▶

 Read News and Comment ▶

Microbiology: Molecular mail by nanotube ▶

 Read News and Comment ▶

Cancer: Cyclin through drug resistance ▶

 Read News and Comment ▶

Immunology: Modulating malaria's mayhem ▶

 Read News and Comment ▶

Molecular biology: When DNA repair goes wrong ▶

 Read News and Comment ▶

Palaeoanthropology: No marathons for Neanderthals ▶

 Read News and Comment ▶

Animal rights and wrongs ▶

A Nature survey shows the pernicious impact of activism on biomedical scientists. More institutions must offer researchers the training they need to stand up for their work. Read News and Comment ▶

Animal testing: TV or not TV? ▶

Two views on whether scientists who believe that animal experimentation is necessary should become public advocates, or work quietly behind the scenes. Read News and Comment ▶

Earth systems: Shaped by life ▶

Wolfgang Lucht sees a lesson for humanity's future in the long co-evolution of our planet and its inhabitants. Read News and Comment ▶

Books in brief ▶

 Read News and Comment ▶

Q&A: Perfumes preserved ▶

Roman Kaiser, a chemist at the Givaudan Research Centre in Dübendorf, Switzerland, has recreated the scents of hundreds of rare and endangered plants in his laboratory, some of which he describes in his latest book. Here he explains how he preserves the smell of disappearing flora. Read News and Comment ▶

Differing opinion, not misconduct ▶

 Steven B. Abramson Read News and Comment ▶

Stuttering studies support treatment ▶

 Mark Onslow, Ann Packman & Peter Howell Read News and Comment ▶

Clarifying relatives and ancestors ▶

 Walter Shearer Read News and Comment ▶

Tax credits help firms ▶

Government programme helped biotechnology companies create and save jobs. Read Careers ▶

Stipend raise proposed ▶

US president's budget includes a boost for postdocs. Read Careers ▶

Stem-cell opportunities ▶

Californian research centre starts recruiting. Read Careers ▶

More News & Comment on Biological Sciences ▶

Transient Hoogsteen base pairs in canonical duplex DNA ▶

Evgenia N. Nikolova, Eunae Kim, Abigail A. Wise, Patrick J. O’Brien, Ioan Andricioaei et al.

Sequence-directed variations in the canonical DNA double helix structure that re... Read Research ▶

Prion propagation and toxicity in vivo occur in two distinct mechanistic phases ▶

Malin K. Sandberg, Huda Al-Doujaily, Bernadette Sharps, Anthony R. Clarke & John Collinge

Mammalian prions cause fatal neurodegenerative conditions including Creutzfeldt|... Read Research ▶

Crystal structure of the CusBA heavy-metal efflux complex of Escherichia coli  ▶

Chih-Chia Su, Feng Long, Michael T. Zimmermann, Kanagalaghatta R. Rajashankar, Robert L. Jernigan et al.

Gram-negative bacteria, such as Escherichia coli, expel toxic chemicals through ... Read Research ▶

Spectroscopy: Unexpected interactions ▶

Ivano Bertini & Claudio Luchinat

Unpaired electrons can exert effects that allow interatomic contacts in molecule... Read Research ▶

Prion diseases: Infectivity versus toxicity ▶

Reed B. Wickner

Prions are infectious proteins that can cause deadly diseases in mammals. Detail... Read Research ▶

Biophysics: Flipping Watson and Crick ▶

Barry Honig & Remo Rohs

Watson–Crick base pairs underpin the DNA double helix. Evidence of trans... Read Research ▶

Chemistry: One catalyst, two products ▶

 Read News and Comment ▶

Environmental chemistry: Tobacco smoke, take three ▶

 Read News and Comment ▶

Chemistry: Enigmatic elements ▶

A Philadelphia exhibition is a playful celebration of the periodic table, reports Katharine Sanderson. Read News and Comment ▶

More News & Comment on Chemical Sciences ▶

An open-system quantum simulator with trapped ions ▶

Julio T. Barreiro, Markus Müller, Philipp Schindler, Daniel Nigg, Thomas Monz et al.

The control of quantum systems is of fundamental scientific interest and promise... Read Research ▶

Submillimetre galaxies reside in dark matter haloes with masses greater than 3 × 1011 solar masses ▶

Alexandre Amblard, Asantha Cooray, Paolo Serra, B. Altieri, V. Arumugam et al.

The extragalactic background light at far-infrared wavelengths comes from optica... Read Research ▶

Geometric frustration in compositionally modulated ferroelectrics ▶

Narayani Choudhury, Laura Walizer, Sergey Lisenkov & L. Bellaiche

Geometric frustration is a broad phenomenon that results from an intrinsic incom... Read Research ▶

Extended megadroughts in the southwestern United States during Pleistocene interglacials ▶

Peter J. Fawcett, Josef P. Werne, R. Scott Anderson, Jeffrey M. Heikoop, Erik T. Brown et al.

The potential for increased drought frequency and severity linked to anthropogen... Read Research ▶

Coupled quantized mechanical oscillators ▶

K. R. Brown, C. Ospelkaus, Y. Colombe, A. C. Wilson, D. Leibfried et al.

The harmonic oscillator is one of the simplest physical systems but also one of ... Read Research ▶

Trapped-ion antennae for the transmission of quantum information ▶

M. Harlander, R. Lechner, M. Brownnutt, R. Blatt & W. Hänsel

More than 100 years ago, Hertz succeeded in transmitting signals over a few metr... Read Research ▶

Climate change: Old droughts in New Mexico ▶

John Williams

A long climate record reveals abrupt hydrological variations during past intergl... Read Research ▶

Fluid dynamics: A turbulent matter ▶

Steven A. Balbus

A long-standing controversy about whether the motions within a typical astrophys... Read Research ▶

Climate change and evolutionary adaptation ▶

Ary A. Hoffmann & Carla M. Sgrò

Evolutionary adaptation can be rapid and potentially help species counter stress... Read Research ▶

Exoplanets: Earth-sized, not Earth-like ▶

 Read News and Comment ▶

Hydrology: Melting to the max ▶

 Read News and Comment ▶

Books in brief ▶

 Read News and Comment ▶

More News & Comment on Physical Sciences ▶

Extended megadroughts in the southwestern United States during Pleistocene interglacials ▶

Peter J. Fawcett, Josef P. Werne, R. Scott Anderson, Jeffrey M. Heikoop, Erik T. Brown et al.

The potential for increased drought frequency and severity linked to anthropogen... Read Research ▶

Seismic tremors and magma wagging during explosive volcanism ▶

A. Mark Jellinek & David Bercovici

Volcanic tremor is a ubiquitous feature of explosive eruptions. This oscillation... Read Research ▶

An armoured Cambrian lobopodian from China with arthropod-like appendages ▶

Jianni Liu, Michael Steiner, Jason A. Dunlop, Helmut Keupp, Degan Shu et al.

Cambrian fossil Lagerstätten preserving soft-bodied organisms have contri... Read Research ▶

Consequences of climate change on the tree of life in Europe ▶

Wilfried Thuiller, Sébastien Lavergne, Cristina Roquet, Isabelle Boulangeat, Bruno Lafourcade et al.

Many species are projected to become vulnerable to twenty-first-century climate ... Read Research ▶

Earth science: Volcanic tremor wags on ▶

Stephen R. McNutt

A new model for volcanic tremor has a magma column, surrounded by gas bubbles, o... Read Research ▶

Climate change: Old droughts in New Mexico ▶

John Williams

A long climate record reveals abrupt hydrological variations during past intergl... Read Research ▶

Climate change and evolutionary adaptation ▶

Ary A. Hoffmann & Carla M. Sgrò

Evolutionary adaptation can be rapid and potentially help species counter stress... Read Research ▶

Hydrology: Melting to the max ▶

 Read News and Comment ▶

Environmental chemistry: Tobacco smoke, take three ▶

 Read News and Comment ▶

Earth systems: Shaped by life ▶

Wolfgang Lucht sees a lesson for humanity's future in the long co-evolution of our planet and its inhabitants. Read News and Comment ▶

Books in brief ▶

 Read News and Comment ▶

More News & Comment on Earth & Environmental Sciences ▶

Career choices: The mobility imperative ▶

Changing labs is crucial for the next generation of European scientists. But mobility can be a mixed blessing. Read Careers ▶

Mobility rethought ▶

Lars H. Breimer, Michael E. Breimer and Douwe D. Breimer say doing a postdoc abroad is unnecessary. Read Careers ▶

Tax credits help firms ▶

Government programme helped biotechnology companies create and save jobs. Read Careers ▶

Stipend raise proposed ▶

US president's budget includes a boost for postdocs. Read Careers ▶

Stem-cell opportunities ▶

Californian research centre starts recruiting. Read Careers ▶

Genzyme deal set to alter biotech landscape ▶

Maintaining innovative culture will be a key challenge for new owners of industry stalwart. Read News and Comment ▶

Postdoctoral Fellowship for study of circulating tumor cells

University of Michigan Ann Arbor, Michigan

Postdoctoral Position in Cell Signaling and Cancer Biology

Boston University School of Medcine Boston, MA

PhD position

Uniklinik Balgrist, University of Zurich, Switzerland Zurich, Switzerland

Research Associate

Loyola University Medical Center Maywood, IL

Barcelona BioMed Conferences: Mitochondrial Autophagy

21.-23.03.11 Barcelona, Spain